Research Affiliate I (Post Doctoral) JR-0001413_[5]
Applications due 4/2/25
This Research Affiliate I position will offer a stimulating professional growth opportunity using innovative molecular biology and microbiology experiments to conduct studies of mycobacteria. The Research Affiliate I will work with the Principal Investigator (PI) to apply their PhD training to study the physiology of mycobacteria using a wide range of molecular biology, microbial genetics, transcriptomics and advanced microscopy.  This will entail working with the Principal Investigator (PI) to design and execute experiments to explore gene expression, horizontal DNA transfer and mycobacterial responses to cell-cell contact. Experiments may include mutagenesis, transcriptomics, structure-function studies of proteins, live-cell fluorescence microscopy and computational analysis of datasets, or the development of customized approaches as the needs of projects progress. The Research Affiliate will also provide support to other lab members and contribute to general lab activities. The Molecular Genetics team focuses on a novel form of horizontal DNA transfer in mycobacteria, and its role in mycobacterial evolution. In particular, they use the unique responses in donor and recipient cells to understand the mechanisms of how mycobacteria distinguish one another upon cell-cell contact and characterize the responses to that contact. Mentoring by the PI will facilitate growth of independence in experimental design and execution on professional development tailored to support the individual in achieving their chosen career goal. This work provides novel insights on mycobacterial cell-cell communication that have been missed in traditional monoculture approaches. [https://www.wadsworth.org/research/laboratories/derbyshire-gray_[6]]. The experimental models provide unique insights into how mycobacteria behave in communities and reach beyond the inherent limitations of conventional studies. We look forward to exploring these frontiers with you. Come and join a highly interactive scientific community focusing on molecular biology of bacteria https://www.wadsworth.org/research/laboratories_[7].

This position will be part of a dynamic team serving the Wadsworth Center’s mission in the New York State Department of Health’s efforts to protect and promote the health of New York’s citizens. Come be a part of Science in the Pursuit of Health®!

Research Scientist 5-Biology Vacancy ID 184030_[8]
Applications due 4/14/25
A Research Scientist 5 is required to serve as the Wadsworth Center ‘s Clinical Laboratory Director. In this role, the Clinical Laboratory Director will oversee the operation and administration of the clinical laboratories located at three different sites in and around Albany, New York. Responsibilities include managing the employment of qualified personnel, ensuring proper delegation and performance of responsibilities, compliance with CLIA and New York State regulations, maintaining quality testing systems, and implementing a quality system approach to ensure accurate and reliable patient test results.

Research Affiliate I Organic Analytical Chemistry JR-0001442_[9]
Applications due 4/7/25
The Research Affiliate I will work with a Principal Investigator to develop their post-doctoral skill set. The incumbent will contribute to developing and validating high-resolution mass spectrometric methods for the analysis of ultra-trace levels of organic chemicals in human and environmental specimens; receive training to perform mass spectrometric data analysis; and be trained to prepare project reports and manuscripts for publication. In addition, through training and mentorship under a Principal Investigator, the Research Affiliate I will be responsible for the operation and troubleshooting of LC-MS/MS and gas chromatography-mass spectrometry (GC-MS) instruments.

This position will be part of a dynamic team serving the Wadsworth Center’s mission in the New York State Department of Health’s efforts to protect and promote the health of New York’s citizens. Come be a part of Science in the Pursuit of Health®!

Senior Laboratory Technician JR-0001369_[10]
Applications due 4/2/25
Health Research Inc. is seeking a Senior Laboratory Technician to work within the Wadsworth Center, New York State Department of Health. The Senior Laboratory Technician will assist with setting up research experiments on the molecular mechanisms of regulation of drug resistance in mycobacteria. The position involves preparing and setting up for the design and creation of gene knockouts, setting up for next generation of mutant bacteria, and data analysis to decipher regulatory pathways that contribute to intrinsic drug resistance in these bacteria. The incumbent will be responsible for learning established procedures, supporting the establishment of new experimental approaches and assist in generating data for publication.

This position will be part of a dynamic team serving the Wadsworth Center’s mission in the New York State Department of Health’s efforts to protect and promote the health of New York’s citizens. Come be a part of Science in the Pursuit of Health®!

Assistant Research Scientist Newborn Screening Program JR-0001495_[11]
Applications due 4/11/25
Health Research, Inc. is seeking an Assistant Research Scientist to work within the Wadsworth Center. https://www.wadsworth.org/_[12]. The Assistant Research Scientist will join a highly interactive team in the Newborn Screening Program at the Wadsworth Center, assisting in validating and setting up a Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) assay for the detection of Metachromatic Leukodystrophy, rolling out the assay in a newborn screening setting and performing day to day screening. The incumbent will test using an LC-MS/MS screening assay. The incumbent will be part of a team serving the primary mission of the New York State Newborn Screening Program, which is to identify newborns with health conditions so that they may receive timely evaluation and treatment.  https://www.wadsworth.org/programs/newborn_[13].

This position will be part of a dynamic team serving the Wadsworth Center’s mission in the New York State Department of Health’s efforts to protect and promote the health of New York’s citizens. Come be a part of Science in the Pursuit of Health®!

Research Scientist I Virology Laboratory JR-0001439_[14]
Applications due 4/12/25
Health Research, Inc. is seeking a Research Scientist I to work within the Wadsworth Center’s Laboratory of Viral Diseases. As a member of the largest state public health Virology laboratory team in the U.S., the Research Scientist I will participate in the detection and characterization of multiple viral pathogens of major public health interest, development of future techniques, as well as contribute to the largest state wastewater surveillance program in the country. Testing will consist of human and wastewater sample analysis, test result importation into an electronic laboratory information system, sequence annotation, and participation in molecular proficiency testing panels.

This position will be part of a dynamic research and development team serving the Wadsworth Center’s mission in the New York State Department of Health’s efforts to protect and promote the health of New York’s citizens. Come, be a part of Science in the Pursuit of Health!

Research Scientist 2 - Mycology Vacancy ID 183339 Biodefense and Mycotic Diseases-Mycology_[15]
Application due 4/4/25
Under the direction of a higher-level scientist, the Research Scientist 2 will devote his/her time to biosafety level 2 and 3 laboratories activities and develop molecular and protein-based based assays and whole-genome sequencing assays for high-risk fungal pathogens. The Research Scientist 2 will also validate molecular and protein-based tests and perform additional duties as required. The incumbent will also perform routine testing of the laboratory, including QC/QA.

Office Assistant 1 Stores and Mail (NY HELPS) Mail, Receiving and Asset Management Vacancy ID 183699_[16]
Applications due 4/10/25
Under direct supervision, the incumbent will provide direct support to Mail, Receiving, and Asset Management at the Wadsworth Center. Responsibilities include receiving shipments containing supplies, equipment, samples/specimens, dangerous goods, and live animals. Process these items both manually and using an electronic purchasing system. Process outgoing correspondence and packages using postage machines and FedEx Ship Manager, as well as any other methods required. The incumbent will also assist with shipping supplies and test kits for the wastewater program. Other duties as assigned.

Research Scientist 2 -Analytical Chemistry Environmental Laboratory Approval Program Vacancy ID 184138_[17]
Applications due 4/16/25
The Wadsworh Centers, Environmental Laboratory Approval Program (ELAP) oversees greater than 400 laboratories that test environmental samples for contaminants that are harmful to public health. ELAP safeguards the accuracy of testing by ensuring laboratory compliance with state and federal regulations. This position requires evaluation of proficiency testing data for all methods and analytes tested by regulated laboratories; communication with regulated laboratories and external entities; assisting the program with updates and revisions to external facing information, including regulation; maintaining documentation and updating the program database; and additional duties as assigned.

Hourly Research Scientist (Internship) JR-0001464_[18]
Applications due 4/3/25
Health Research, Inc. is seeking an Hourly Research Scientist to work within the Division of Translational Medicine at the Wadsworth Center of the New York State Department of Health to assist in the implementation of a novel purification method to isolate ribosomes from small volumes of cell culture. Ribosomes are protein-synthesizing molecular machinery that are a primary target of antibiotics used to treat bacterial diseases. Recently, a technique called RAPPL (RNA Affinity Purification using Poly-Lysine) has been developed as a simple, cost-effective, and rapid method to purify active ribosomes from small cell culture volumes. The incumbent will assist in optimizing this method for purifying ribosomes from Escherichia coli (Eco) cell cultures, assess its efficacy of purification to previous ribosome purification methods such as sucrose fractionation, and then apply it to purify ribosomes from other cell cultures, such as Mycobacterium smegmatis (Msm). The work may involve activities including but not limited to ordering supplies, buffer preparation, bacterial cell culture, ultra-centrifugation, sucrose fractionation, RNA gel separation, protein gel separation, cryo-electron electron microscopy grid preparation, and related biochemical assays. This is a great opportunity to learn cutting-edge techniques used in scientific research that is geared towards solving major public health issues.

This position is part of the Pathways to Public Health Internship Program.  This position will last approximately 10 weeks from 6/2/2025 to 8/8/2025.  It is made available through funding from the Center for Disease Control's Public Health Infrastructure Grant to expand opportunities to strengthen career pathways to public health by bringing together students of all disciplines and academic levels with public health professionals to create a space of exploration, learning, and development.