Diagnostic Immunology - Testing

Bacterial Serology

• Anaplasma phagocytophilum IgG IFA
• Bartonella henselae and quintana IgG IFA
• Borrelia burgdorferi ELISA
  • B. burgdorferi VlsE1/pepC10 IgG/IgM Screen with reflex
  • B. burgdorferi IgG and IgM when Screen is positive or equivocal
• Brucella abortus IgG-IgA-IgM Tube Agglutination
• Coxiella burnetii (Q Fever) Phase 1 and Phase 2 IgG IFA
• Ehrlichia chaffeensis IgG IFA
• Rickettsia IgG and IgM IFA (Spotted Fever and Typhus Fever groups)
• Treponema pallidum (syphilis)
  • RPR and TPPA
    • By consultation only.
    • No routine screening available.
  • VDRL Cerebrospinal Fluid (CSF)

Parasitic Serology

• Babesia microti IgG-IgM-IgA IFA

Viral Serology

• Arbovirus Screen, CSF*
  • West Nile IgM ELISA
• Arbovirus Screen, Serum* includes:
  • West Nile IgM ELISA
  • Arbovirus IgG-IgM-IgA Microsphere Immunofluorescence Assay (MIA)
    • includes West Nile and Powassan serology
  • Powassan IgM ELISA (if Powassan MIA result is reactive)
  • Arbovirus IgG IFA includes:
    • Eastern Equine Encephalitis
    • Western Equine Encephalitis
    • St. Louis Encephalitis
    • California Serogroup Encephalitis
• Chikungunya IgG and IgG ELISA, Serum*
• Flavivirus Screen, Serum*
  • Flavivirus IgG-IgM-IgA Microsphere Immunofluorescence Assay (MIA)
    • includes Zika and Dengue serology
  • Zika IgM Lateral Flow

*When encephalitis PCR is also requested for any arbovirus

• Freeze at least 1.0 mL of CSF and/or serum
• Ship on dry ice directly to the Viral Encephalitis Laboratory (VEL).
• Specimens will be forwarded by VEL to DIL
   

Vaccine Preventable Disease

Contact your local county health department for approval prior to submitting the following:

• Measles - IgG and IgM ELISA, active disease
• Mumps - IgG ELFA and IgM IFA, active disease
• Rubella - IgG ELFA and IgM ELISA, active disease

Immune Status Serology

• Immunity testing for measles, mumps, and rubella is available for local and state health department employees only.

Centers for Disease Control (CDC) Referrals

• Specimens for referral to the CDC must be submitted to state health departments for appropriate processing.  The Diagnostic Immunology Laboratory will forward specimens from NYS residents to the CDC.  Instructions for submitting specimens can be found at https://www.cdc.gov/laboratory/specimen-submission/index.html
• Please complete the NYS Infectious Disease Requisition, https://www.wadsworth.org/programs/id/idr.

Please call the lab at 518-486-3845 with questions.