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Did you know that you only need a few drops of dried blood from a pricked finger to test for COVID-19 antibodies? Indeed, not only does a drop of blood contain a multitude of different antibodies to viruses and other microbes, but Wadsworth Center scientists are able to measure an array of different types of antibodies and estimate how well they are able to fight off an infection.  Such technologies represent the interaction of clinical testing and research investigation that occur at the Center every day of the week.

Read how Wadsworth Center scientists adapted the tools they already had to increase COVID surveillance capacity.

Wadsworth Center is committed to the continuing education of the next generation of public health laboratorians. In partnership with the Association of Public Health Laboratories (APHL) and the Centers for Disease Control and Prevention (CDC), Wadsworth Center has offered full-time, working fellowships to graduate and post-graduate scientists for more than 25 years.

See Governor Hochul's April 21, 2022 press release.

Tuberculosis­­­ - The Tortoise Would you be surprised to know that tuberculosis (TB) was the leading infectious disease killer in the world in 2019? Estimates of deaths attributed to TB were second only to COVID-19 in 2020 (roughly 1.5 million versus 1.8 million reported deaths, respectively). In the ongoing race to be the microbe responsible for the largest number of deaths across the planet, “hares” like HIV and SARS-CoV-2 explode onto the scene and appear to leave everyone else in the dust.

Wadsworth Center joins with the Association of Public Health Laboratories to celebrate Lab Week April 24-30, 2022. Follow the links to learn about the many ways public health laboratorians help to keep us safe every day - from environmental testing to infectious disease testing to newborn screening.

Please see New York State Department of Health Press Release More about COVID-19 Variant Data

A culmination of work in Lyme arthritis in patients and in animal models, the review highlights the paradigm that infectious agents may trigger immune dysregulation and autoimmunity, leading to persistent post-infectious sequelae.Lyme arthritis: linking infection, inflammation and autoimmunity.Lochhead RB, Strle K, Arvikar SL, Weis JJ, Steere AC. Nat Rev Rheumatol. 2021 Aug;17(8):449-461. doi: 10.1038/s41584-021-00648-5. Epub 2021 Jul 5. PMID: 34226730 Review.Cover used courtesy Springer Nature Limited.

Rachel Fay, Ph.D. candidate in Wadsworth Center’s Arbovirology Laboratory, under the mentorship of Dr. Alex Ciota, took first place in the University at Albany’s fourth annual Three Minute Thesis competition with her talk titled, “Increasing the resolution of vector-borne diseases and climate change”. The contest gives all graduate students across all fields at the University at Albany a chance to present their work. Listen to Rachel’s talk.

Dr. Nicholas Mantis, of Wadsworth Center's Division of Infectious Diseases, was awarded a five-year, $9 million contract by the National Institute of Allergy and Infectious Diseases (NIAID) to study human antibody responses to the Lyme disease pathogen, Borrelia burgdorferi.  

​Current antibiotics work by interfering with bacterial growth, which is a fine game plan… until it stops working. More and more, bacteria are finding ways around this approach, resulting in a huge antibiotic resistance problem. Dr. Jon Paczkowski may just have come up with a new defensive strategy and recently received a five-year grant from the National Institutes of Health to investigate.

As we’ve seen repeatedly during the pandemic, it isn’t always easy to get our hands on everything we need, hmmm, cue the toilet paper, especially new things. This reality translates to addressing patients who have COVID today. By using tools we already have in labs across the country, we can capitalize on the technology, instruments and the know how to use them by using them in new ways.

Dr. St. George is quoted in the feature article beginning on page 5 and our own Infectious Disease Fellow Nora Cleary is featured on pg 19. Nora has been selected for the Edith Hsiung Memorial prize for her abstract/presentation on Hep A whole genome sequencing.  This is one of the two top travel awards from the American Society for Microbiology for a student, fellow, or technologist, presenting their work at the annual, international Clinical Virology Symposium, to be held this year in West Palm Beach.

Having spent a lot of time in our homes recently, most of us are probably contemplating a dream renovation. If that project requires several professionals - plumbers, electricians, carpenters, etc., we might have second thoughts.

Read on page 26 of Association of Public Health Laboratories' Fall/Winter Lab Matters Issue about Wadsworth Center's Collaboration with CDC's Biodefense Research and Development Laboratory.

In 2019, cases of a mysterious illness related to vaping, formally referred to as “e-cigarette or vaping product use-associated lung injury” (EVALI), were identified across the United States.  A significant number of cases affected young New Yorkers.  In association with NY Regional Poison Control Centers and medical facilities from around the state, Wadsworth Center’s Laboratory of Organic Analytical Chemistry analyzed vape fluid samples from suspected cases for cannabinoids, pesticides, synthetic cannabinoids, opioids, illicit drugs, an

SARS-CoV-2, like all viruses, is constantly creating new variants through mutation of its RNA genome. Most mutations are of little or no consequence. However, every once in a while, a new mutation can increase transmissibility, increase disease severity, cause the virus to escape the body’s immune response, or do any combination of these.

The World Health Organization estimates that almost 4,000 people lose their lives to TB and close to 28,000 people contract TB every day.  Currently, 13 million people in the United States live with latent (hidden) TB infection.

The Association of Public Health Laboratories (APHL) is pleased to announce the winners of its annual awards (page 32) for outstanding achievements in laboratory science, creative approaches t

Infections with Mycobacterium tuberculosis (Mtb),  the etiological agent of tuberculosis (TB) in humans, are difficult to eradicate with antibiotics: a 6-month long multidrug regimen is necessary for the treatment of TB.  The drug recalcitrance of TB infections has been associated with a specialized subpopulation of Mtb cells, that do not replicate or are very slow growing and whose metabolism is significantly decreased.